For oral communications (including slides of lectures and posters), click here or scroll until after the publications.
See also my Google scholarSelected contributions
Predicting survival in patients with
advanced NSCLC treated with atezolizumab using pre- and on-treatment prognostic
biomarkers
S. Benzekry, M. Karlsen, C. Bigarré, A. El Kaoutari, B. Gomes, M. Stern, A. Neubert, R. Bruno, F.
Mercier, S.
Vatakuti, P. Curle and Candice Jamois.
Clinical Pharmacology and Therapeutics, 116, 1110–1120, medRxiv,
2024
Comprehensive
biomarkers (BMs) analysis to predict efficacy of PD1/L1 immune checkpoint inhibitors (ICIs) in combination
with chemotherapy: a subgroup analysis of the Precision Immuno-Oncology for advanced Non-Small CEll Lung
CancER (PIONeeR) trial
F. Barlesi, et al., S. Benzekry
Annals
of Oncology, 16 (suppl_1), 2022
Artificial
intelligence and mechanistic modeling for clinical decision making in oncology
S. Benzekry
Clinical Pharmacology and Therapeutics, Volume 108, Issue 3, pp.471-486, 2020
Mechanistic modeling of metastatic relapse in early breast cancer to investigate
the biological impact of prognostic biomarkers
C. Bigarre, F. Bertucci, P. Finetti, G. MacGrogan, X. Muracciole*, S. Benzekry. *
= joint senior authors
Computer Methods and Programs in Biomedicine, 231, 107401, hal, 2023
Machine learning and mechanistic
modeling for prediction of metastatic relapse in breast cancer
C. Nicolo, C. Perier, M. Prague, G. MacGrogan, O. Saut, S. Benzekry
JCO: Clinical Cancer Informatics, Volume 4, pp. 259-274, bioRxiv, 2020
Contributions in Mathematical
Oncology: When Theory Meets Reality
HDR (Habilitation à diriger des recherches) thesis, defended November 13th, 2017
Modeling spontaneous metastasis
following surgery: an in vivo-in silico approach
S. Benzekry, A. Tracz, M. Mastri, R. Corbelli, D. Barbolosi, J.M.L. Ebos
Cancer Research, Volume 76, Issue 3, pp. 535-547, hal, 2016
Mathematical modeling of
tumor-tumor distant interactions supports a systemic anti-proliferative control of tumor
growth
S. Benzekry, C. Lamont, D. Barbolosi, L. Hlatky, P. Hahnfeldt
Cancer Research, Volume 77, Issue 18, pp.5183-5193, 2017
Quantitative
mathematical modeling of clinical brain metastasis dynamics in non-small cell lung cancer
M. Bilous, C. Serdjebi, A. Boyer, P. Tomasini, C. Pouypoudat, D. Barbolosi, F. Barlesi, F. Chomy and S.
Benzekry
Scientific Reports, Volume 9, Issue 1, 13018, bioRxiv, hal, 2019
Classical Mathematical Models for Description and Forecast of Preclinical Tumor Growth
S. Benzekry, C. Lamont, A. Beheshti, A. Tracz, J.M.L. Ebos, L. Hlatky, P. Hahnfeldt
PLoS Computational Biology, Volume 10, Issue 8, e1003800, 2014
Revisiting bevacizumab +
cytotoxics scheduling using mathematical modeling: proof of concept study in experimental non-small cell
lung carcinoma
D.C. Imbs*, R. El Cheikh*, A. Boyer, J. Ciccolini, C. Mascaux, B. Lacarelle, F. Barlesi,
D. Barbolosi and S. Benzekry, * = equal contribution
CPT Pharmacometrics Syst Pharmacol, Volume 7, Issue 1, pp. 42-50, hal, 2018
Population modeling of tumor growth curves and the reduced Gompertz model improve prediction
of the age of experimental tumors
C. Vaghi, A. Rodallec, R. Fanciullino, J. Ciccolini, J. Mochel, M. Mastri, C. Poignard, J. ML Ebos, S.
Benzekry
PLoS Computational Biology, Volume 16, Issue 2, e1007178, bioRxiv, 2020
Computational modelling of
metastasis development in renal cell carcinoma
E. Baratchart, S. Benzekry*, A. Bikfalvi*, T. Colin*, L.S. Cooley, R.
Pineau, E. Ribot, O. Saut, W. Souleyreau, * = joint supervising authors
PLoS Computational Biology, Volume 11, Issue 11, e1004626, hal, 2015
Journal articles
-
Predicting survival in patients
with
advanced NSCLC treated with atezolizumab using pre- and on-treatment prognostic
biomarkers
S. Benzekry, M. Karlsen, C. Bigarré, A. El Kaoutari, B. Gomes, M. Stern, A. Neubert, R. Bruno, F. Mercier, S. Vatakuti, P. Curle and Candice Jamois.
Clinical Pharmacology and Therapeutics, 116, 1110–1120 medRxiv, doi.org/10.1002/cpt.3371, 2024 -
Machine-learning and mechanistic modeling of primary and metastatic breast
cancer
growth after neoadjuvant targeted therapy
S. Benzekry, M. Mastri, C. Nicolo, J. ML Ebos
PLoS Comp Biol, bioRxiv, 2024 -
A senescence-mimicking (senomimetic) VEGFR TKI side-effect primes tumor immune
responses via IFN/STING signaling
M. Dolan, Y. Shi, M. Mastri, M. D Long, A. McKenery, J. W. Hill, C. Vaghi, S. Benzekry, J. J Barbi and J. M. L. Ebos
Mol Cancer Ther, 24, 1241–1260 doi:10.1158/1535-7163.mct-24-0139, 2024 -
Computational
markers
for personalized prediction of outcomes in non-small cell
lung cancer patients with brain
metastases
S. Benzekry*, P. Schlicke*, P. Tomasini, E. Simon. * = joint first authors
Clin Exp Metastasis, 41(1):55-68, medRxiv, 2024 -
Mechanistic Learning for Predicting Survival
Outcomes in Head and Neck Squamous Cell Carcinoma
K. Atsou, A. Auperin, J. Guigay, S. Salas, S. Benzekry
accepted in CPT Pharmacometrics Syst Pharmacol, hal, 2024 -
Computational modeling for circulating
cell-free DNA in clinical oncology
L. Nguyen-Phuong, S. Salas, S. Benzekry
accepted in JCO: Clin Cancer Informatics, hal 2024 -
Acquired resistance
to
PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor
cells
Y. Shi, M. Dolan, M. Mastri, J. W. Hill, A. Dommer, S. Benzekry, K. Eng, J. ML Ebos
EMBO Reports, bioRxiv, 2024 -
Role of PCI for
patients with extensive stage small cell lung cancer in the immunotherapy era: real-life data report
over the period 2014 to 2021.
A. Daumas, C. Bigarre, M. Boucekine, A. Zaccariotto, A. Mogenet, E. Gouton, J. Pluvy, P. Tomasini, X. Muracciole, S. Benzekry, L. Greillier and L. Padovani
accepted in Cancers, 2024 -
Mechanistic modeling of metastatic relapse in early breast cancer to investigate
the biological impact of prognostic biomarkers
C. Bigarre, F. Bertucci, P. Finetti, G. MacGrogan, X. Muracciole*, S. Benzekry. * = joint senior authors
Computer Methods and Programs in Biomedicine, 231, 107401, hal, 2023 -
Reuniting Philosophy and
Science to Advance Cancer Research
T. Pradeu,... S. Benzekry,..., L. Laplane
Biological Reviews, 2023 -
Une comparaison des algorithmes
d'apprentissage
pour la survie avec données manquantes
P. Dufossé, S. Benzekry
arXiv, 2023 -
Practical identifiability analysis of a mechanistic model for the time to distant
metastatic
relapse and its application to renal cell carcinoma
A. Alvarez-Arenas, W. Souleyreau, A. Emanuelli, L.S. Cooley, JC Bernhard, A. Bikfalvi, and S. Benzekry
PLoS Computational Biology, 18(8): e1010444, 2022 -
Tumor
growth monitoring in breast cancer xenografts: a good technique for a strong ethic
A. Rodallec, C. Vaghi, J. Ciccolini, R. Fanciullino, and S. Benzekry
PLoS One, 17(9): e0274886, 2022 -
Des
modèles mathématiques pour la recherche clinique en cancérologie
S. Benzekry
Interstices, 2022
-
Macro-scale models
for
fluid flow in tumour tissues: impact of microstructure properties
C. Vaghi, R. Fanciullino, S. Benzekry, C. Poignard
Journal of Mathematical Biology, Volume 84, Issue 27, bioRxiv, 2022 -
Asymptotic analysis of a biphase tumor fluid flow: the weak coupling case
C. Vaghi, S. Benzekry, C. Poignard
Appl Math Comput, Volume 413, 126635, 2022 -
Machine learning for prediction of
immunotherapy efficacy in non-small cell lung cancer from simple clinical and biological
data
S. Benzekry, M. Grangeon, M. Karlsen, M. Alexa, I. Bicalho-Frazeto, S. Chaleat, P. Tomasini, D. Barbolosi, F. Barlesi, L. Greillier
Cancers, Volume 5, pp. 81-90, medRxiv, 2021 -
Development and Validation
of a
Prediction Model of Overall Survival in High-Risk Neuroblastoma Using Mechanistic Modeling of
Metastasis
S. Benzekry, C. Sentis, C. Coze, L. Tessonnier, N. André
JCO: Clin Cancer Informatics, Volume 5, pp. 81-90, medRxiv, 2021 -
Experimental and computational modeling for signature and biomarker discovery of renal
cell
carcinoma progression
L. Cooley, J. Rudewicz, W. Souleyreau, A. Emmanuelli, A. Alvarez-Arenas, K. Clarke, F. Falciani, M. Dufies, D. Lambrechts, E. Modave, D. Chalopin-Fillot, R. Pineau, D. Ambrosetti, J-C Bernhard, A. Ravaud, S. Negrier, J-M Ferrero, G. Pages, S. Benzekry, M. Nikolski, A. Bikfalvi
Molecular Cancer, 20, bioRxiv, 2021
-
Artificial
intelligence and mechanistic modeling for clinical decision making in oncology
S. Benzekry
Clinical Pharmacology and Therapeutics, Volume 108, Issue 3, pp.471-486, 2020 -
Machine learning and
mechanistic
modeling for prediction of metastatic relapse in breast cancer
C. Nicolo, C. Perier, M. Prague, G. MacGrogan, O. Saut, S. Benzekry
JCO: Clinical Cancer Informatics, Volume 4, pp. 259-274, bioRxiv, 2020
-
Population modeling of tumor growth curves and the reduced Gompertz model improve
prediction
of the age of experimental tumors
C. Vaghi, A. Rodallec, R. Fanciullino, J. Ciccolini, J. Mochel, M. Mastri, C. Poignard, J. ML Ebos, S. Benzekry
PLoS Computational Biology, Volume 16, Issue 2, e1007178, bioRxiv, 2020 -
Mechanistic learning for
combinatorial strategies with immuno-oncology drugs: can model-informed designs help
investigators?
J. Ciccolini, D. Barbolosi, N. André, F. Barlesi, S. Benzekry
JCO: Precision Oncology, , Volume 4, pp. 486-491, 2020
-
Quantitative
mathematical modeling of clinical brain metastasis dynamics in non-small cell lung
cancer
M. Bilous, C. Serdjebi, A. Boyer, P. Tomasini, C. Pouypoudat, D. Barbolosi, F. Barlesi, F. Chomy and S. Benzekry
Scientific Reports, Volume 9, Issue 1, 13018, bioRxiv, hal, 2019
-
Is There Any Room for
Pharmacometrics With Immuno-Oncology Drugs? Input from the EORTC-PAMM Course on Preclinical and
Early-phase Clinical Pharmacology
A. Rodallec, R. Fanciullino, S. Benzekry, J. Ciccolini, EORTC PAMM group
Anticancer Research, Volume 39, Issue 7, p. 3419-3422, hal, 2019
-
Optimal
Scheduling of Bevacizumab and Pemetrexed/cisplatin Dosing in Non-Small Cell Lung Cancer
B. K Schneider, A. Boyer, J. Ciccolini, F. Barlesi, K. Wang, S. Benzekry* and J. P Mochel*, * = joint senior authors
CPT Pharmacometrics Syst Pharmacol, Volume 25, hal, 2019
-
CAR T-Cell
Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological
Malignancies
J. P Mochel, S. C Ekker, C. M Johannes, A. E Jergens, K. Allenspach, A. Bourgois-Mochel, M. Knouse, S. Benzekry, W. Wierson, A. K LeBlanc, S. S Kenderian
AAPS J, Volume 21, Issue 3, p.50, hal, 2019
-
Turning cold tumors into hot
tumors:
harnessing the potential of tumor immunity using nanoparticles
A. Rodallec, G. Sicard, R. Fanciullino, S. Benzekry, B. Lacarelle, G. Milano, J. Ciccolini
Expert Opin Drug Met, Volume 14, Issue 11, p. 1139-1147, 2018
-
Revisiting
bevacizumab +
cytotoxics scheduling using mathematical modeling: proof of concept study in experimental non-small
cell
lung carcinoma
D.C. Imbs*, R. El Cheikh*, A. Boyer, J. Ciccolini, C. Mascaux, B. Lacarelle, F. Barlesi, D. Barbolosi and S. Benzekry, * = equal contribution
CPT Pharmacometrics Syst Pharmacol, Volume 7, Issue 1, pp. 42-50, hal, 2018
-
Dose- and time-dependence of the
host-mediated
response to paclitaxel therapy: a mathematical modeling approach
M. Benguigui, D. Alishekevitz, M. Timaner, D. Shechter, Z. Raviv, S. Benzekry*, Y. Shaked*, * = joint senior authors
Oncotarget, Volume 9, pp.2574-2590, 2018
-
Pharmacokinetics of
nanoparticles
in oncology: clues for anticipating interpatient variability
R. Fanciullino, S. Benzekry, B. Lacarelle, J. Ciccolini, A. Rodallec
Critical Reviews in Oncology/Hematology, Volume 129, pp. 1-12, hal, 2018
-
Mathematical modeling of tumor-tumor distant interactions supports a systemic control
of
tumor growth
S. Benzekry, C. Lamont, D. Barbolosi, L. Hlatky, P. Hahnfeldt
Cancer Research, Volume 77, Issue 18, pp.5183-5193, 2017
-
Non-Standard Radiotherapy Fractionations Delay the Time to Malignant Transformation of
Low-Grade Gliomas
A. Henares-Molina, S. Benzekry, P.C. Lara, M. Garcia-Rojo, V.M. Perez-Garcia and A. Martinez-Gonzalez
PLoS One, Volume 12, Issue 6, e0178552, hal, 2017
-
Model Driven Optimization of
Antiangiogenics + Cytotoxics Combination: Application to Breast Cancer Mice Treated with Bevacizumab +
Paclitaxel Doublet Leads to Reduced Tumor Growth and Fewer Metastasis
S. Mollard, J. Ciccolini, D.C. Imbs, R. El Cheikh, D. Barbolosi, S. Benzekry
Oncotarget, Volume 5, 10.18632/oncotarget.15484, 2017
-
In vivo bioluminescence tomography for
monitoring breast tumor growth and metastatic spreading: comparative study and mathematical
modeling
S. Mollard, R. Fanciullino, S. Giacometti, C. Serdjebi, S. Benzekry, J. Ciccolini
Scientific Reports, Volume 6, pp.36173, 2016
-
Mathematical modeling of cancer immunotherapy
and
synergy with radiotherapy
R. Serre, S. Benzekry, L. Padovani, C. Meille, N. André, J. Ciccolini, F. Barlési, X. Muracciole, and D. Barbolosi
Cancer Research, Volume 76, Issue 17, pp. 4931–40, 10.1158/0008-5472.CAN-15-3567, 2016
-
Modeling spontaneous metastasis following
surgery: an in vivo-in silico approach
S. Benzekry, A. Tracz, M. Mastri, R. Corbelli, D. Barbolosi, J.M.L. Ebos
Cancer Research, Volume 76, Issue 3, pp. 535-547, 10.1158/0008-5472.CAN-15-1389, 2016
-
Computational modelling of
metastasis development in renal cell carcinoma
E. Baratchart, S. Benzekry*, A. Bikfalvi*, T. Colin*, L.S. Cooley, R. Pineau, E. Ribot, O. Saut, W. Souleyreau, * = joint supervising authors
PLoS Computational Biology, Volume 11, Issue 11, e1004626, hal, 2015
-
Metronomics reloaded: theoretical models
bringing
chemotherapy into the era of precision medicine
S. Benzekry+, E. Pasquier+, D. Barbolosi, B. Lacarelle, F. Barlesi, N. Andre and J. Ciccolini
Seminars in Cancer Biology, Volume 35, pp. 53-61, 10.1016/j.semcancer.2015.09.002, 2015
-
Design Principles for Cancer
Therapy
guided by changes in complexity of Protein-Protein Interaction Networks
S. Benzekry , J.A. Tuszynski, E.A. Rietman, G.L. Klement
Biology Direct, Volume 10, Issue 32, 2015
-
Host Age is a Systemic Regulator of Gene Expression Impacting Cancer
Progression
A. Beheshti, S. Benzekry, J.T. MacDonald, L. Ma, M. Peluso, P. Hahnfeldt, L. Hlatky
Cancer Research, Volume 75, Issue 6, pp. 1134-43, 2015
-
Classical Mathematical Models for Description and Forecast of Preclinical Tumor
Growth
S. Benzekry, C. Lamont, A. Beheshti, A. Tracz, J.M.L. Ebos, L. Hlatky, P. Hahnfeldt
PLoS Computational Biology, Volume 10, Issue 8, e1003800, 2014
-
Global Dormancy of Metastases due to Systemic Inhibition of Angiogenesis
S. Benzekry, A. Gandolfi, P. Hahnfeldt
PLoS One, Volume 9, Issue 1, e84249, 2014
-
Maximum Tolerated Dose Versus Metronomic
Scheduling in the Treatment of Metastatic Cancers
S. Benzekry, P. Hahnfeldt
Journal of Theoretical Biology, Volume 335, pp. 235-244, 2013
-
Theoretical investigation of the efficacy of
antiangiogenic drugs combined to chemotherapy in xenografted mice
F. Lignet, S. Benzekry, S. Wilson, F. Billy, O. Saut, M. Tod, B. You, A. Adda Berkane, S. Kassour, M.X. Wei, E. Grenier, B. Ribba
Journal of Theoretical Biology, Volume 320, pp. 86-99, 2013
-
Modelling the impact of anticancer agents on
metastatic spreading
S. Benzekry, N. André, A. Benabdallah, J. Ciccolini, C. Faivre, F. Hubert and D. Barbolosi
Mathematical Modeling of Natural Phenomena , Volume 7, Issue 1, pp. 306 - 336, 2012
-
A new mathematical model for
optimizing the combination between antiangiogenic and cytotoxic drugs in oncology
S. Benzekry, G. Chapuisat, J. Ciccolini, A. Erlinger and F. Hubert
Comptes Rendus de l'Académie des Sciences - Mathématiques, Volume 350, Issue 1-2, pp. 23-28, 2012
-
Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic
cancers
S. Benzekry
ESAIM: Mathematical Modelling and Numerical Analysis, Volume 46, Issue 2, pp. 207-237, hal, 2012.
-
Passing to
the
limit 2D-1D in a model for metastatic growth
S. Benzekry
Journal of Biological Dynamics, Volume 6, Suppl. Issue 1, pp. 19-30, hal, 2011
-
Mathematical
analysis
of a two-dimensional population model of metastatic growth including angiogenesis,
S. Benzekry
Journal of Evolution Equations Volume 11, Issue 1, pp. 187-213, hal, 2011
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
Book chapters, editorials, proceedings and protocols
- Comprehensive
biomarkers (BMs) analysis to predict efficacy of PD1/L1 immune checkpoint inhibitors (ICIs) in combination
with chemotherapy: a subgroup analysis of the Precision Immuno-Oncology for advanced Non-Small CEll Lung
CancER (PIONeeR) trial.
Slides
F. Barlesi, et al., S. Benzekry
Annals of Oncology, 16 (suppl_1), 2022
- Supporting decision making and early
prediction of survival for oncology drug development using a pharmacometrics-machine learning based
model.
S. Benzekry, M. Karlsen, A. El Kaoutari, R. Bruno, A. Neubert, F. Mercier, M. Stern, B. Gomes, S. Vatakuti, P. Curle and Candice Jamois.
PAGE 30, Abstr 10276, 2022
-
Abstract
LB120: Comprehensive biomarkers analysis to explain resistances to PD1-L1 ICIs: The precision
immuno-oncology for advanced non-small cell lung cancer (PIONeeR) trial
L. Greillier et al., S. Benzekry, J. Fieschi, F. Barlesi
Cancer Res, 82 (12_Supplement): LB120, 2022
-
Abstract
2737: A mechanistic model for prediction of metastatic relapse in early-stage breast cancer using routine
clinical features
C. Bigarré, P. Finetti; F. Bertucci; X. Muracciole, S. Benzekry
Cancer Res, 82 (12_Supplement): 2737, 2022
-
Abstract
3195: Hijacked senescence secretomes as 'immune primers' of antiangiogenic TKI efficacy
M. Dolan, Y. Shi, J. W. Hill, M. Mastri, C. Vaghi, J. Barbi, S. Benzekry, J. M. Ebos
Cancer Res, 81 (13_Supplement): 3195, 2021
-
Mechanistic models for hematological
toxicities: Small is beautiful
L. Deyme, S. Benzekry, J. Ciccolini
CPT: Pharmacometrics Syst Pharmacol, Volume 10, Issue 5, pp. 396-398, 2021
-
Abstract
5493: Mathematical modeling of antibody nanoconjugates transport quantifies the impact of the tumor
microenvironment on drug penetration
C. Vaghi, A. Rodallec, G. Sicard, F. Correard, R. Fanciullino, J. Ciccolini, C. Poignard, S. Benzekry
Cancer Res, 80 (16_Supplement): 5493, 2020
-
Abstract
6244: Turning poorly vascularized tumors into highly vascularized tumors with nanoparticles: Proof of
concept and pharmacometric analysis
G. Sicard, A. Rodallec, F. Correard, C. Vaghi, C. Poignard, J. Ciccolini, S. Benzekry, A. Sergé, R. Fanciullino
Cancer Res, 80 (16_Supplement): 6244, 2020
-
Deciphering the response and resistance to
immune-checkpoint inhibitors in lung cancer with artificial intelligence-based analysis: the PIONeeR and
QUANTIC joint-projects
J. Ciccolini, S. Benzekry, F. Barlesi
British Journal of Cancer, 2020
-
Prédiction de l’efficacité de
l’immunothérapie dans le cancer bronchique à partir de données cliniques et biologiques simples : apport
de l’intelligence artificielle
M. Grangeon, S. Benzekry, S. Chaleat, P. Tomasini, D. Barbolosi, F. Barlesi, L. Greillier
Revue des Maladies Respiratoires, Volume 12, Issue 1, pp. 217, hal, 2020
-
Combinatorial immunotherapy strategies: most
gods throw dice, but fate plays chess
J. Ciccolini, N. Andre, D. Barbolosi, S. Benzekry, F. Barlesi
Annals of Oncology, Volume 62, Issue 2, hal, 2019
-
Population Modeling
of Tumor Growth Curves, the Reduced Gompertz Model and Prediction of the Age of a Tumor.
C. Vaghi, A. Rodallec, R. Fanciullino, J. Ciccolini, J. Mochel, M. Mastri, J. ML Ebos, C. Poignard and S. Benzekry
In G. Bebis, T. Benos, K. Chen, K. Jahn, & E. Lima (Eds.), (pp. 87–97). Presented at the Mathematical and Computational Oncology, Cham: Springer International Publishing, 2019
-
Abstract
4264: Mathematical modeling of differential effects of Sunitinib on primary tumor and metastatic
growth.
C. Nicolo, M. Mastri, J. ML Ebos, S. Benzekry
Cancer Research, Volume 78, Issue 13 (Supplement), 4264, 2018
-
Etude de
l’effet séquence bevacizumab/pemetrexed/cisplatine chez la souris porteuse de cancer du poumon non
à petites cellules.
A. Boyer, J. Ciccolini, C. Mascaux, D.C. Imbs, R. El Cheikh, F. Barlesi, and S. Benzekry
Revue des Maladies Respiratoires, 34:A52, 2017
-
Abstract 4529:
Optimization of the sequence for the administration of bevacizumab in combination with pemetrexed and
cisplatin in NSCLC : a pharmacology based in vivo study
A., Boyer, D.C. Imbs, R.E. Cheikh, C. Mascaux, F. Barlesi, D. Barbolosi, S. Benzekry, and J.
Ciccolini.
Cancer Research, Volume 77, Issue 13 (Supplement), 4529, 2017
-
Optimized
radiotherapy protocols delay the malignant transformation of low-grade gliomas in-silico
A. Henares-Molina, S. Benzekry, P. Lara, M. García-Rojo, V. Pérez-García, and A. Martínez-González
Neuro-Oncology, 19 (suppl 3):iii12–iii12, 2017
-
Les lois de la croissance tumorale
S. Benzekry
Bibliothèque Tangente, Hors-série Maths et Médecine, 2016
-
Next generation metronomic chemotherapy—report from the Fifth Biennial International
Metronomic and Anti-angiogenic Therapy Meeting, 6–8 May 2016, Mumbai.
Pantziarka, P., Hutchinson, L., André, N., Benzekry, S., Bertolini, F., Bhattacharjee, A., et al.
ecancermedicalscience, 10, 2016
-
On the growth and dissemination laws in a
mathematical model of metastatic growth
S. Benzekry, J. ML Ebos
ITM Web of Conferences, Volume 5, 10.1051/itmconf/20150500007, 2015
-
Improving efficacy
of the combination between antiangiogenic and chemotherapy: Time for mathematical modeling
support
J. Ciccolini, S. Benzekry, B. Lacarelle, D. Barbolosi and F. Barlési
Proc Natl Acad Sci USA, Volume 112, Issue 27, 10.1073/pnas.1506689112, 2015
-
Capturing the Driving Role of Tumor-Host Crosstalk in
a Dynamical Model of Tumor Growth
S. Benzekry, A. Beheshti, P. Hahnfeldt, L. Hlatky
bio-protocol, Volume 5, Issue 21, e1644, hal, 2015
-
Abstract 3677:
Model-based optimization of combined antiangiogenic + cytotoxic modalities: application to the
bevacizumab-paclitaxel association in breast cancer models
S. Mollard, S. Benzekry, S. Giacometti, C. Faivre, F. Hubert, J. Ciccolini and D. Barbolosi.
Cancer Research, Volume 74, Issue 19 (Supplement), 3677, 2014
-
A Mathematical Model
for Growing Metastases on Oncologists’s Service
D. Barbolosi, A. Benabdallah, S. Benzekry, J. Ciccolini, C. Faivre, F. Hubert, F. Verga, B. You
In Computational Surgery and Dual Training, Springer New York, pp. 331-338, 2014
-
A mathematical model of
systemic inhibition of angiogenesis in metastatic development
S. Benzekry, A. Gandolfi, P. Hahnfeldt
ESAIM: Proceedings, Volume 45, pp. 75-87, 2014
Foreign research visits
Fall 2016. Short sabbatical at the Roswell Park Cancer Institute to work with John ML Ebos, Buffalo, NY, USA.September 2015. Invited researcher in the Môlab to work with Alicia Martinez-Gonzalez and Victor Pérez-Garcia, Ciudad Real, Spain.
January 2012 - November 2012. Postdoc at the Center of Cancer and Systems Biology, Boston, USA.
May 2011. Instituto di Analisi dei Sistemi ed Informatica ''Antonio Ruberti'', Consiglio Nazionale delle Ricerche. Research visit with Alberto Gandolfi and collaboration with Alberto d'Onofrio, from the European Institute of Oncology from Milan. Rome, Italy.
March - June 2007. Master 2’s intership in the mathematical department of the Polytechnical University of Catalonia : Exploration of deterministics and stochastics neuronal reds. Barcelona, Spain.
Invited talks
- September, 2024. Twelfth International Workshop on Pharmacodynamics of Anticancer Agents. "Use of machine learning for predicting cancer outcomes", Ponta Delgada, Portugal.
- July, 2024. ECMTB congress (European Conference on Mathematical and Theoretical Biology). "Mechanistic learning for metastasis modeling and prediction", talk within the mini-symposium "Mechanistic learning in mathematical oncology" organized by A. Kohn-Luque and S. Haupt, Toledo, Spain.
- July, 2024. ECMTB congress (European Conference on Mathematical and Theoretical Biology). "Integrating kinetics and machine learning modeling for prediction of outcome following immunotherapy in lung cancer", talk within the mini-symposium "Digital twins for clinical oncology and cancer research" organized by G. Lorenzo, Toledo, Spain.
- July, 2024. SMB congress (Society of Mathematical Biology). "Integrative kinetics and machine learning modeling for prediction of outcome following immunotherapy in lung cancer". Talk within the mini-symposium "Mathematical modeling of cancer treatment" organized by E. Kim, Seoul, Korea.
- June, 2024. BIOMAT summer school. Mini-course "Mechanistic learning to predict response and survival in immuno-oncology.", Granada, Spain.
- March, 2024. Keynote invited speaker in the session "Machine Learning for Rare Disease Applications: from Limited to In Silico Trials" of the Applied machine learning days (AMLD2024), "Mechanistic learning to predict the results of clinical trials", EPFL, Lausanne.
- January, 2024. EORTC-PAMM, The PIONeeR trial, Marseille.
- October, 2023. Workshop for young researchers in Cancer, invited as keynote speaker, Cancéropôle PACA, Porquerolles.
- July, 2023. SMB congress (Society of Mathematical Biology). Talk within the mini-symposium "modeling approaches used to study cancer treatment." organized by K. Wilkie and G. Powathil. L. Nguyen et al., S. Benzekry, Mechanistic modeling of the longitudinal tumor and biological markers combined with quantitative cell-free DNA. Ohio State University, OH, USA.
- June, 2023. Annual meeting of the APHM center for early phase clinical trials in oncology, Marseille, France.
- June, 2023. Annual congress of the French group of clinical pneumo-oncology (GPCO), Toulon, France.
- June, 2023. Annual congress of the French society of pharmacology and therapeutics (SFPT), Limoges, France.
- May, 2023. SMAI congress (French Society of Applied and Industrial Mathematics). Talk within the mini-symposium "Modélisation Mathématique du cancer et de son environnement" organized by F. Hubert and M. Mezache. Pointe à Pitre, France.
- January, 2023. CARe graduate school workshop, Numerical and technical tools to better investigate metabolism, inflammation and cancer. Toulouse, France.
- May, 2022. 8th international conference on Systems Biology of Mammalian Cells: From Systems Medicine towards Digital Health, Heidelberg, Germany
- April, 2022. Quantitative systems pharmacology conference, Leiden, The Netherlands
- March, 2022. MI Day " Immunotherapies & Lung Cancer : predictive biomarkers from The PIONeeR Project ", Marseille, France
- January, 2022. Workshop on tissue growth and movement. Poincaré institute, Paris, France
- October, 2021. Multidisciplinary Approaches in Cancer Research. Sophia Antipolis, France
- June, 2021. Annual seminar of the regional Canceropole Provence-Alpes Cote d'Azur. COMPO: COMPutational pharmacology and clinical Oncology.
- June, 2021. Mini-symposium "Mathematical approaches to advance clinical studies in oncology", Society of Mathematical Biology annual Conference.(online). Quantitative modeling of metastasis: cancer at the organism scale. (Slides)
- December, 2020. Workshop on Mathematical modelling in the machine learning era. Göteborg, Sweden (online conference).
- May, 2020, CIMPA Research Summer School on Mathematical models applied to molecular dynamics and oncology. Santiago de Cuba, Cuba.
-
April 2020, 10th European Lung Cancer Congress (ELCC). Geneva, Switzerland.
-
January, 2020, Second philosophy of cancer workshop. Quantitative modeling of metastasis: cancer at the
organism scale. Bordeaux, France. (Slides)
-
July 2019, International
Society of Pharmacometrics (ISoP) workshop. Paris, France. (Slides)
-
May 2019, Masterclass Mathematiques appliquees CEPS Mathematiques Des Sciences du Vivant, CIRM, Marseille,
France. Data-driven mechanistic modeling of metastasis: cancer at the organism scale.
-
May 2019, NCI
Mathematical Oncology Meeting, Portland, USA. Machine learning versus mechanistic modeling for
prediction of metastatic relapse in breast cancer.(Slides)
-
May 2019, RITS conference (Recherche en
Imagerie et Technologies pour la Sante) of the French Society of Biomedical Engineering (SFGBM), Tours,
France. Data-driven mechanistic modeling of metastasis: cancer at the organism scale. (Slides)
-
November 2018, Mathematical Challenges in the Analysis of Continuum Models for Cancer Growth, Evolution and
Therapy, Oaxaca, Mexico. (Slides)
-
July 2018, Mathematical
perspectives in the biology and therapeutics of cancer, Marseille, France. (Slides)
-
July 2018, Annual
Workshop on Mathematics in Medicine, Wolfgang Pauli Institute, Vienna, Austria. (Slides)
-
June 2018, 3rd Mathematical
Biology Modelling Days, Besançon, France. (Slides)
-
February 2018, CMM-Fields-Inria Workshop on Mathematics for Medicine, Toronto, Canada.
-
January 2018, Conference on Statistics and Health, Toulouse, France.
-
December 2017, Mathematical methods and modeling of biophysical phenomena. Mathematical modeling and
prediction of metastasis. Rio de Janeiro, Brazil.
-
September 2017, Première session du GDR MAMOVI. Mathematical Modeling and Prediction of Clinical Brain Metastases in Non-Small
Cell Lung Cancer. Lyon, France
-
June 2017, XXV Congreso de ecuaciones diferenciales y
aplicaciones / XV congreso de matematica aplicada, Optimization of the timing of sequential
administration of bevacizumab plus cytotoxics in non-small cell lung cancer by a mathematical model.
Cartagena, Spain.
-
May 2016, Metronomics @ Mumbai. Mathematical modeling of chemotherapy scheduling.
Mumbai, India.
-
December 2015, Present challenges of
mathematics in oncology and biology of cancer. Marseille, France.
-
November 2015, Dynamique et contrôle des
croissances tumorales, Rouen, France.
-
November 2015, Contrôle des EDP et
applications , Marseille, France.
-
October 2015, Journées du Groupe de Métabolisme et
Pharmacocinétique , Paris, France.
-
June 2015, Micro and Macro Systems in Life Sciences
(MMSLS 2015), Bedlewo, Poland.
-
March 2015, Workshop on
hybrid and multiscale modelling in cell and cell population biology
, Laboratoire Jacques-Louis Lions. Combined in vivo and in silico quantitative modeling of post-surgery
metastatic development. Paris, France.
-
March 2015, Mathematical Methods and Modeling
of Biophysical Phenomena, Cabo Frio, Rio de Janeiro, Brazil.
-
January 2015, 36th EORTC PAMM Winter meeting , Marseille,
France.
-
October 2014, Autumn School by Japanese and
French Mathmaticians . Mathematical modeling of tumor growth and metastatic spread. Data, theories and
predictions. Osaka, Japan.
-
July 2014, 10th AIMS Conference on
Dynamical Systems, Differential Equations and Applications . A mathematical model of systemic inhibition
of angiogenesis in metastatic development. Madrid, Spain.
-
November 2013, French-Mexican Meeting on
Industrial and Applied Mathematics, Villahermosa, México. Classical Mathematical Models for Description
and Forecast of Preclinical Tumor Growth
-
May 2013, Bi-annual congress of the SMAI.
Mathematical modeling of systemic inhibition of angiogenesis and metastatic dynamics. Seignosse, France.
-
March 2013, Workshop on Mathematical Methods
and Modeling of Biophysical Phenomena, Cabo Frio, Brazil. Mathematical modeling of systemic inhibition
of angiogenesis and metastatic dynamics
-
July 2012, 2nd Annual Workshop on Cancer Systems Biology — Tumor Metronomics: Timing and Dose Level
Dynamics, Center for Cancer and Systems
Biology, Boston. Mathematical modeling of
metastatic development and scheduling optimization of anti-cancerous therapies
-
March 2012, Thematic school : "Present
challenges of mathematics in oncology and biology of cancer", CIRM, Marseille. A modeling approach for therapies in metastatic cancers
-
October 2011, Journées du Groupe de Métabolisme et Pharmacocinétique. Paris. Poster and
Oral communication, Biomathematical modeling for
description of metastatic processes and optimization of combined anti-angiogenic + cytotoxic therapies.
-
July 2011, Workshop on Systems Biology of Tumor Dormancy. St. Elizabeth's Medical Center, Boston USA. A modelling approach for therapies in metastatic
cancers.
-
July 2011, 7th Congrès International Congress on Industrial and Applied Mathematics - ICIAM 2011, Vancouver.
Mathematical modeling of the metastatic process and optimization
of anti-cancerous therapies.
-
May 2011, ``Emergence'' day of the Institut Gustave Roussy (IGR).Un exemple de modélisation du processus métastatique. Paris, France.
-
June 2010, CANUM 2010, A model of metastatic growth under
angiogenic control. Gironde, France.
-
May 2010, AIMS Dresde. Modeling and mathematical analysis of
metastatic growth under angiogenic control. Dresden, Germany
-
March 2010, 2nd Workshop on Metronomic Anti-Angiogenic Chemotherapy in Paediatric Oncology. Mathematical
modeling of MTD and metronomic temozolomide. Marseille, France.
Seminars (invited)
- April, 2025. Mechanistic learning for predicting resistance and survival in immune-checkpoint inhibition therapy. Center for Computational Oncology, UT Austin, Texas, USA.
- March, 2024. Mechanistic learning for clinical cancer research. CANSEARCH, Geneva University, Switzerland.
- May, 2023. Séminaire : Modélisation numérique et application en médecine clinique. Ajaccio, France.
- January, 2023. EMD Serono, Cambridge, MA USA. Invited by I. Kareva.
- February, 2022. Seminar in the bioinformatics group of the CRCM.
- October, 2021. Seminar at the Center for Cancer Research of Marseille. Mechanistic learning : combining mechanistic modeling and statistical learning to predict outcome in clinical oncology. Marseille, France
-
June 2021, Seminar at the Centre de recherches en cancérologie de Toulouse (CRCT). Quantitative modeling of
metastasis: cancer at the organism scale.
-
May 2021, Seminar at the pharmacometrics group of Merck. COMPO - COMPutational pharmacology and clinical
Oncology: Optimization of therapeutic strategies by mechanistic and statistical modeling.
-
Apr 2021, Seminar of the Pharma - Informatics
Unit of the Athena research group, Athens, Greece. COMPO - COMPutational pharmacology and clinical
Oncology.
-
Mar 2021, Applied statistics seminar of the mathematics department. Marseille, France. COMPO - COMPutational
pharmacology and clinical Oncology.
-
Jan 2021, Biomathematics seminar of the mathematics department. Marseille, France. COMPO - COMPutational
pharmacology and clinical Oncology.
-
June 2019, Seminar in the Novartis pharmacometrics department. Basel, Switwerland. Artificial intelligence and
machine learning in oncology: myths and reality.
-
May 2019, Biomedicum Helsinki Seminar (Invitation by Sampsa Hautaniemi), Faculty of Medicine, Helsinki, Finland.
-
May 2019, Seminaire phases I en oncologie, Marseille, France. Old concept, new name? l’intelligence
artificielle en oncologie.
-
November 2018, Probability and Statistics seminar, Institut Elie Cartan de Lorraine, Nancy, France.
-
February 2018, Seminar at the Roswell
Park Cancer Institute (Invitation by Dr. J. Ebos), Buffalo, USA.
-
December 2017, Seminar at the Rappaport Faculty of
Medicine of the Technion Israel Institute of
Technology (invitation by Yuval Shaked). Contributions in Mathematical Oncology: When Theory Meets Reality. Haifa,
Israel.
-
May 2017, Laboratoire d'Analyse Topologie et
Probabilites, Institut de Mathematiques de Marseille. Mathematical Oncology: Theory Meets Reality.
Marseille, France.
-
November 2016, Integrated Mathematical Oncology
Department, Moffitt Cancer Center.Mathematical Modeling of Metastasis: Theory Meets Reality. Tampa,
Florida, USA.
-
October 2016, Department of Genetics, Roswell Park Cancer Institute (invitation by John ML Ebos). Mathematical Modeling of
Metastasis: Theory Meets Reality. Buffalo, NY, USA.
-
October 2016, Robert
Kerbel's laboratory at Sunnybrook Research Institute. Mathematical Modeling of Metastasis: Theory Meets
Reality. Toronto, Canada.
-
October 2016, Mathematics Department
Colloquium, Ryerson University. Mathematical Modeling of Metastasis: Predicting the invisible. Toronto,
Canada.
-
May 2016, Seminar at the laboratory of Génétique,
Immunothérapie, Chimie et Cancer of the University of Tours. Data-based mathematical modeling analysis
of preclinical studies in oncology. Tours, France.
-
January 2016, Seminar at the laboratoire
d'imagerie biomédicale. Classical Mathematical Models for Description and Prediction of Experimental
Tumor Growth. Paris, France.
-
March 2014, Seminar at the Inria team Dracula.
Classical Mathematical Models for Description and Prediction of Experimental Tumor Growth. Lyon, France.
-
April 2013, Seminar of the ANEDP team .
Mathematical modeling of systemic inhibition of angiogenesis and metastatic dynamics. Orsay, France.
-
February 2013, Seminar of the LATP, Marseille,
France. A math walk in a biology lab
-
November 2011, EDP seminar of the mathematics lab in Besançon. Modélisation et analyse mathématique de thérapies anti-cancéreuses pour les cancers
métastatiques
-
May 2011, Seminar at the Instituto di Analisi dei Sistemi ed Informatica ``Antonio Ruberti'', Rome. A modelling approach for the metastatic process.
-
May 2010, Seminar Maths-Bio of the university Lyon 1. Modeling
and mathematical analysis of metastatic growth under angiogenic control. Lyon, France
Accepted oral communications
-
September 2024, ESMO,
Paris, France.
Long circulating-free DNA fragments predict early-progression (EP) and
progression-free
survival (PFS) in advanced carcinoma treated with immune-checkpoint inhibition (ICI): A new biomarker.
Salas, S., Nguyen-Phuong, L., Ginot, F., Greillier, L., Tomasini, P., Boutonnet, A., Deville, J.L., Fina, F. and Benzekry, S.
ESMO, Ann. Oncol., 35, S270, Poster, 2024. -
July 2024, Control
release society, Bologna, Italy.
PK/PD modelling to advance the preclinical development of a novel polymer prodrug in oncology
A. Rodallec, R. Lee, S. Marolleau, S. Benzekry*, J. Nicolas*, * = joint senior authors
CRS, Poster, 2024. -
June 2024, PAGE, Roma, Italy.
Mechanistic modelling of tumor kinetics coupled with biomarker dynamics for survival prediction in non-small
cell lung
cancer patients
R. Taieb, R. Bruno, J. Jin, P. Chanu, S. Benzekry
PAGE, 32, Abstr 10812, Oral, 2024. -
June 2024, PAGE, Rome, IT.
Circulating cell-free DNA size distribution as a prediction marker for early progression undergoing immune
checkpoint
inhibitors
L. Nguyen Phuong, F. Fina, L. Greillier, C. Gaudy-Marqueste, J.L. Deville, J.C. Garcia, S. Salas, S. Benzekry
PAGE, 32, Abstr 11111, Poster, 2024 -
June 2024, ASCO, Chicago, USA.
Long cell-free DNA fragments predict early-progression in patients with advanced or metastatic cancer treated
with
immune-checkpoint inhibition
Salas, S., Phuong, L.N., Garcia, J.-C., Greillier, L., Gaudy-Marqueste, C., Deville, J.-L., Boutonnet, A., Ginot, F., Fina, F., and Benzekry, S.
ASCO, J. Clin. Oncol., 42, e14550–e14550, Abstract, 2024. -
June 2024, ASCO, Chicago, US.
Mathematical modelling of routine biological parameters kinetics in order to predict durable benefit for
first-line
immunotherapy in metastatic or unresectable melanoma
J. Forestier, A. Daumas, C. Gaudy-Marqueste, S. Benzekry*, N. Malissen*, * = joint senior authors
ASCO, J. Clin. Oncol., 42, e21549–e21549, 2024 -
June 2024, JOBIM, Toulouse, FR.
Immune landscapes and metabolic profiles in Neuroblastoma
H. Hamdache, V. Pancaldi* and S. Benzekry*, * = joint senior authors
JOBIM, 2024 -
November 2023, SITC, Paris, France. Regulatory
T-cell tumor infiltration improves advanced NSCLC patients’ outcome under ≥ 2nd line anti-PD1/L1 monotherapy
in The PIONeeR Project. Poster
M. Landri, ..., S. Benzekry, ..., J. Fieschi
Journal for ImmunoTherapy of Cancer 11, A1813–A1813, 2023
-
December 2022, ESMO-IO, Geneva, Switzerland. Comprehensive
biomarkers (BMs) analysis to predict efficacy of PD1/L1 immune checkpoint inhibitors (ICIs) in combination
with chemotherapy: a subgroup analysis of the Precision Immuno-Oncology for advanced Non-Small CEll Lung
CancER (PIONeeR) trial.
Oral
F. Barlesi, et al., S. Benzekry
ESMO IO, Abstr 3MO, 2022
-
June 2022, 30th population approaches group in Europe (PAGE) conference, Ljubljana, Slovenia. Supporting decision making and early
prediction of survival for oncology drug development using a pharmacometrics-machine learning based
model. Oral
S. Benzekry, M. Karlsen, A. El Kaoutari, R. Bruno, A. Neubert, F. Mercier, M. Stern, B. Gomes, S. Vatakuti, P. Curle and Candice Jamois.
PAGE 30, Abstr 10276, 2022
-
April 2022, AACR conference, New Orleans, USA. Comprehensive biomarkers
analysis to explain resistances to PD1-L1 ICIs: The precision immuno-oncology for advanced
non-small cell lung cancer (PIONeeR) trial. Poster
L. Greillier, ..., S. Benzekry, J. Fieschi, F. Barlesi.
AACR, Abstr LB120, 2022
-
April 2022, AACR conference, New Orleans, USA.A
mechanistic model for prediction of metastatic relapse in early-stage breast cancer using routine
clinical features
C. Bigarré, P. Finetti, F. Bertucci, X. Muracciole, S. Benzekry
AACR, Abstr. 2737, 2022
-
March 2022, World conference on pharmacometrics (WCOP), Cape Town, South Africa.
Pharmacometrics modeling coupled with machine learning for early prediction of overall survival following atezolizumab monotherapy in non-small cell lung cancer. Poster
S. Benzekry, M. Karlsen, A. El Kaoutari, S. Vatakuti, P. Curle and Candice Jamois -
March 2022, World conference on pharmacometrics (WCOP), Cape Town, South Africa.
Machine learning for prediction of immunotherapy efficacy in non-small cell lung cancer from simple clinical and biological data. Poster
S. Benzekry, M. Grangeon, M. Karlsen, M. Alexa, I. Bicalho-Frazeto, S. Chaleat, P. Tomasini, D. Barbolosi, F. Barlesi, L. Greillier -
July 2021, AACR, online, US.
Hijacked senescence secretomes as 'immune primers' of antiangiogenic TKI efficacy. Poster
M. Dolan, Y. Shi, J.W. Hill, M. Mastri, C. Vaghi, J. Barbi, S. Benzekry, J. M.L. Ebos
Cancer Res, 81 (13_Supplement):3195, 2021 - December 2020, Workshop on cancer adaptive therapy models. Examples of pharmacometrics studies in preclinical and clinical oncology: mathematical models in concrete therapeutic applications. Moffitt Cancer Center, Tampa, Florida, USA (online conference). (Slides). (Youtube video)
-
August 2020, Virtual Physiological Human 2020
(VPH2020), Paris, France. Descriptive and prognostic value of a computational model of metastasis in
high-risk neuroblastoma. Oral
-
June 2019, Population Approach Group meeting in Europe (PAGE), Stockholm, Sweden. Machine learning versus
mechanistic modeling for prediction of metastatic relapse in breast cancer. Oral
-
June 2019, Population Approach Group meeting in Europe (PAGE), Stockholm, Sweden. Machine learning combined to
mechanistic modeling of differential effects of neo-adjuvant Sunitinib on primary tumor and metastatic
growth. Oral (senior author, first author and speaker C. Nicolo)
-
August 2018, 17th Biennial Congress of the Metastasis Research Society, Princeton, NJ, USA. A
biologically-based mathematical model for prediction of metastatic relapse. Poster.
-
July 2018, Mathematical perspectives in the
biology and therapeutics of cancer, Marseille, France. Improving intra-tumor drug distribution of
anti-cancer nanoparticles by data-informed mathematical modeling. Oral (senior author, first author C. Vaghi).
-
June 2018, Data science summer
school, Polytechnique, Palaiseau, France. Improving intra-tumor drug distribution of anti-cancer
nanoparticles by data-informed mathematical modeling. Poster (senior author, first author C. Vaghi. Won the best poster award)
-
June 2018, Data science summer
school, Polytechnique, Palaiseau, France. Poster
-
May 2018, Population
Approach Group in Europe (PAGE) meeting, Montreux, Switzerland. Modeling Primary Tumor Dynamics of
Human-to-Mouse Xenografted Non-Small Cell Cancer in Response to Administration of Bevacizumab and
Pemetrexed-Cisplatin. Poster (co-senior author
with J. Mochel, first author B. Schneider).
-
April 2018, Annual meeting of the AACR, Chicago, USA. Mathematical modeling of differential effects of
Sunitinib on primary tumor and metastatic growth. Poster (senior author, first author C. Nicolo).
-
March 2017, 38th EORTC-PAMM Winter meeting, Split, Croatia.
Optimization of the timing of sequential administration of bevacizumab plus cytotoxics in NSCLC by a
mathematical model.
-
October 2015, Journées du cancéropôle Grand Sud-Ouest , Bordeaux, France. Poster. Modeling spontaneous
metastasis following surgery: an in vivo-in silico approach
-
June 2015, Mathematical Methods in Systems Biology,
Dublin, Ireland.
-
June 2014, European Conference on Mathematical and Theoretical
Biology , Göteborg, Sweden. Metastatic dynamics, systemic inhibition of angiogenesis and implications
for surgery
-
June 2014, International Tumor Dormancy Symposium , Lille, France. Metastatic dynamics and systemic
inhibition of angiogenesis. Implications for dormancy and surgery (Poster)
-
February 2014, Demonstration during the
inria-industry meeting, Lyon, France. Mathematical Models in Preclinical Cancer Research
-
January 2014, Seminar at the ISPED. Classical
Mathematical Models for Description and Forecast of Preclinical Tumor Growth. Bordeaux, France.
-
June 2011, 8th European Conference on Mathematical and Theoretical Biology - ECMTB 2011 and Annual Meeting of
The Society for Mathematical Biology, Kraków. Optimal schedules for therapies in metastatic cancers .
-
May 2010, CMPD 3, Bordeaux. Modeling and mathematical analysis
of
metastatic growth under angiogenic control.
-
November 2009, Conference of biomathematics et biomechanics, Tozeur, Tunisie. Presentation of a poster.
-
August 2009, CEMRACS. Asymptotic behavior of the solutions of the renewal equation and Angiogenesis modeling.
-
June 2009, Bucolic days of the student's seminar of the LATP.
-
November 2008, Workgroup Maths-Cancer of Marseille. About the article "A theoretical study of the response of
vascular tumours to
different types of chemotherapy" de J. Panovska, H. M. Byrne et P. K. Maini.
Participation to conferences and summer schools
6-8 June 2011, Biomat 2011, Perspectives in Mathematics and Life Sciences.3-4 Février 2011, Journées Louis Antoine "Nonlocal equations and population adaptive dynamics".
2 December 2010. Thematic day "Models and imaging in oncology", Paris, France.
30 November - 1er December 2009. Symposium "Health and complex systems" of the Entretiens Jacques Cartier, Lyon, France.
20-23 November 2009. Conference of biomathématics et biomechanics, Tozeur, Tunisie.
20 July - 28 August 2009. CEMRACS'09 Mathematical modeling in Medicine. Project Angio. CIRM, Marseille, France.
2 - 13 February 2009. Advanced courses and conferences in mathematical biology : modeling and differential equations. CRM, Barcelone, Espagne.
18 - 19 December 2008. Pharmacokinetics and pharmacodynamics of anticancerous drugs : resistances and synergies. Centre de recherche des cordeliers, Paris.