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The team ~ Praveen Pankajakshan Tuesday, June 25th 2024, 10:21

Praveen Pankajakshan

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Former PhD Student

motcle Keywords : Variational methods, MCMC, Wavelets, Parameter Estimation, Deconvolution, 3D Reconstruction
projets Project : P2R France-Israel
demos Demo : see this author's demo
plus Contact :

Mail :praveendotpankajakshanatinriadotfr
Phone :(33)4-92-38-78-63
Fax :(33)4-92-38-76-43
Postal adress :INRIA Sophia Antipolis
2004, route des Lucioles
06902 Sophia Antipolis Cedex
Webpage :visit !

plus Abstract :

I am currently working on the parametric blind deconvolution of Confocal Laser Scanning Microscope (CLSM) images. The CLSM is an optical fluorescence microscope that scans sections of a specimen in 3D and uses a pinhole to reject most out-of-focus light. However, the quality of confocal microscope images suffers from two basic physical limitations.
First, out-of-focus blurs due to the diffraction-limited nature of the optical microscope and secondly, the confocal pinhole drastically reduces the amount of photons detected by the photomultiplier causing poisson noise. The images produces by the CLSM can therefore benefit from post processing by deconvolution methods designed to reduce the blur and noise.
Our current goal is to develop a fast and efficient algorithm for
simultaneous estimation of the point-spread function (PSF) of the microscope and the specimen function. We realize that a good estimation of the PSF is very important for restoration of the original specimen.
However, estimation of the PSF is an undetermined problem with no known unique solution. We overcome this problem by using a physical acquisition model of the microscope and by introducing a priori knowledge about the specimen. This stabilizes the estimation procedure and helps in deciding
between candidate solutions.

plus Last publications in Ariana Research Group :
Wavefront sensing for aberration modeling in fluorescence MACROscopy.
P. Pankajakshan and A. Dieterlen and G. Engler and Z. Kam and L. Blanc-Féraud and J. Zerubia and J.C. Olivo-Marin. In Proc. IEEE International Symposium on Biomedical Imaging (ISBI), Chicago, USA, April 2011.
Keywords : fluorescence MACROscopy , phase retrieval, field aberration.
Point-spread function model for fluorescence MACROscopy imaging.
P. Pankajakshan and Z. Kam and A. Dieterlen and G. Engler and L. Blanc-Féraud and J. Zerubia and J.C. Olivo-Marin. In Asilomar Conference on Signals, Systems and Computers, pages 1364-136, Pacific Grove, CA, USA , November 2010.
Keywords : fluorescence MACROscopy , point-spread function, pupil function, vignetting .
Blind Deconvolution for Confocal Laser Scanning Microscopy.
P. Pankajakshan. PhD Thesis, Universite de Nice Sophia Antipolis, December 2009.
Keywords : Confocal Laser Scanning Microscopy, Blind Deconvolution, point spread function, Maximum likelihood estimation , total variation regularization.
publis All publications in Ariana Research Group
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