Mathieu Desroches
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MTSN
Multiple-Timescale Systems in Neuroscience
A 10-week graduate course (under construction)
1. The Hodgkin-Huxley model and its reductions
◔ Basics of ODEs and phase-plane analysis
[pdf]
◔ Lecture
[pdf]
◕ Readings
[Hodgkin and Huxley (1952)]
[Morris and Lecar (1981)]
[Rinzel (1985)]
[Moehlis (2006)]
◔ Lab 1
[ipynb]
◔ Lab 2
[pdf]
[ipynb]
[solution]
◔ Exercise session 1
[pdf]
[solution]
◔ Exercise session 2
[pdf]
[solution]
2. Bifurcations and neuronal excitability
◔ Lecture 1
[pdf]
◔ Lecture 2
[pdf]
◕ Readings
[Prescott et al. (2008)]
◔ Lab
[pdf]
[ipynb]
3. Integrate-and-fire models
◔ Lecture
[pdf]
◕ Readings
[Brette and Gertsner (2005)]
[Brunel and van Rossum (2007)]
[Ermentrout (2008)]
◔ Exercises
[pdf]
[ipynb]
4. Spiking in slow-fast systems
◔ Lecture
[pdf]
◕ Readings
[FitzHugh (1961)]
[Nagumo et al. (1962)]
◔ Lab
[ipynb]
◔ Exercise
[pdf]
[solution]
5. Bursting in slow-fast systems
◔ Lecture 1
[pdf]
◔ Lecture 2
[pdf]
◕ Readings
[Rinzel (1986)]
[Rinzel and Ermentrout (1998)]
[Izhikevich (2000)]
◔ Lab
[ipynb]