Variant CJD -2
Neuropathology (biopsy and/or PM) showed the characteristic features of CJD in all cases, but amyloid plaques were very prominent
Molecular analysis of PrP shows a distinct pattern (type 4) different from other types of CJD
10 cases described April 1996 (Lancet 347 921-948)
16 further definite vCJD cases up to Dec 1997; 1 case in France, others all UK
total vCJD cases (pobable or definite) 84, Sep 2000
all British axcept 1 Irish and 2 French