About me

Since April 2010, I am a PhD student in science (Signal and image processing) in Morphème research group, a joint team-project of I3S, INRIA and IBV, at Sophia Antipolis.

My PhD supervised by Laure Blanc-Féraud deals with blind restoration of 3D Confocal Laser Scanning Microscopy (CLSM) images. The CLSM is an optical fluorescence microscope which allows to observe 3D biological living specimen at a resolution of about 100 nm. One challenging problem in this imaging system is the depth-variant blur due to refractive index mismatch between the different mediums composing the system. Our goal is thus to simultaneously estimate the depth variant blur function as well as the specimen function. This problem is known to be undetermined because of the non-uniqueness of the solution. To overcome this problem, a priori knowledge about the specimen and the blur functions need to be included in order to stabilize the solution. For that, we rely on another imaging system that can be associated with the CLSM system, called diffractive tomography which provides us with such information.

This work is supported by the ANR DIAMOND project.

Key words

Blind restoration, diffractive tomography, fluorescence microscopy, JMAP, PSF, space-variant blur, total variation, 3D reconstruction

News and events

PhD defense on March 2013.