Nicholas Ayache is currently co-editor-in-chief of the Medical Image Analysis Journal (MedIA) (Elsevier), alongside Jim Duncan (Professor at Yale).

He has also served as associate editor or editorial board member for the following journals:

• IEEE Transactions on Medical Imaging : Associate Editor
• Mathematical Modelling and Numerical Analysis (M2AN) : Editorial Board Member (2007-2010)
• Siam Journal of Imaging Sciences : Associate Editor
• International Journal of Computer Vision (Kluwer) : Honorary Board Member
• Computer Aided Surgery (Wiley) : Editorial Board Member
• Videre-Computer Vision Research Journal (MIT-Press) : Consulting Editor
• Medical Imaging Technology (Japanese Society of Medical Imaging) : Consulting Editor