The globin Family

The globin family contains proteins from many different organisms. Their amino-acid homology can be as low as 16 %. However, their 3D structure is still related and constitutes the globin fold. It is mainly constituted of alpha helices that form a pocket for the active site, which in myoglobins and hemoglobins binds a heme group.


Examples of globins (The heme is displayed in red)

Yellow lupin leghemoglobin


Sea lamprey hemoglobin


Human hemoglobin, chain A


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