Registration of multimodal medical images

Grégoire Malandain

We have two images to register. The first one is a MRI image of 120 slices of 256x256 pixels of the brain (voxels are isotropic, of size 1.3x1.3x1.3 mm) with no inter-slice distance. We can easily segment the brain in this image, using mathematical morphology and topological operators.


Some original slices of the MRI data.

We have also a PET image of 7 slices of 256x256 pixels of the same patient (the voxel size is 1x1x9 mm) with an inter-slice distance of 3 mm. These data are obviously anisotropic. The brain is segmented by a single threshold of this image.


Some original slices of the PET data.

After registration, we resampled the MR data to present the MR slices corresponding to the PET ones.


Some resampled MR slices, corresponding to the PET ones presented above.

We extracted the edges of two of these resampled MR slices and superimposed them on the PET slices:


Superimposition of MR edges on PET slices.

Images are courtesy of Dr. Jael Travere of Cyceron center (CEA, Caen, France).

See the related publications for details.

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Grégoire Malandain
Last modified: Wed Dec 16 10:58:07 MET 1998