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Industrial Collaborations

Registration of patents

  1. "Recalage par rapport de corrélation"
  2. Participant: Alexis Roche, Grégoire Malandain, Nicholas Ayache, Xavier Pennec

    We developed a new registration method based on maximising the correlation ratio (the ratio is at a maximum when the images are perfectly aligned) between two images, which can be multimodal. Following this work, a request for a French patent ("dispositif électronique de recalage automatique d'images", or "electronic device for automatic image registration") was made on 28th July 1998, under the number 9809649, at INPI.

  3. "Diagrammes de décision binaires"
  4. Participants: Grégoire Malandain, Luc Robert

    Following work with Luc Robert on using binary decision diagrams for processing images, a request for a patent ("dispositif de traitement de données d'aquisition, notamment de données d'image", or "device for treatment of acquired data, especially image data" ) was made on 25th June 1998, under the number 9808087.

Elf-Atochem

Participants: Gérard Subsol, Gr�oire Malandain

In this one year project, the Epidaure Project will test several image processing tools on 3D images of chemical structures.

Quantificare

Participants: Nicholas Ayache, Grégoire Malandain, Hervé Delingette, Xavier Pennec

Quantificare has been funded in 2001 by J-P. Thirion, a former researcher of the Epidaure team. Several software including yav++ have been transfered to Quantificare.

General Electric Medical Systems

Participants: Grégoire Malandain, Karl Krissian, Nicholas Ayache

This contract involves the study of segmentation of 3d angiographic data. The precise aim is to understand the topology of the vascular network around an aneurism, in order to improve its treatment. To do this, we have developed tools enabling segmentation by filtering and by discrete topology.

INSERM / Medtronic

Participants: Gérard Subsol, Sébastien Ourselin

This 3 year contract starts at the end of 1998, and involves three bodies:

The aim is to improve the localisation of the target of stimulation of basal ganglia in the treatment of Parkinson's disease, by matching MRI scans of the patient to an anatomical atlas

Nycomed

Participants: Grégoire Malandain, Alexis Roche, Karl Krissian

The aim was to compensate for the motion of the patient in relation to the ultrasound probe, whilst a temporal series of ultrasound pictures was being obtained.

Due to the poor quality of the data, the detection of stable characteristics, and methods of registration which are based on intensity, do not work.

We have shown that it is possible to improve the quality of a temporal series of images by using a 3d anisotropic filter. Furthermore, we can use one of the 2d images from this series as a reference image, and register other images from the non-filtered series with it. This compensates for motion in the entire series of images.

Philips Research France

Participants: Hervé Delingette, Nicholas Ayache

The collaboration started in 1998 with a two year contract for which the library libsimplex, including algorithms for deformable surface models, was transfered. Further collaboration was established regarding the image segmentation of the left ventricle (ICEMA collaborative action).

Data Proxima

Participant: Hervé Delingette,

The software library libsimplex was transfered to Data Proxima and Thermodyn for a 3 years period. It is used as software component in computer-aided design system of gas turbines.

Sanofi-Synthelabo

Participant: Gérard Subsol

This was an 8 month study, launched in October 1997. The aim was to experiment, starting with 3d MRI scans provided by Sanofi-Recherche, with algorithms for treatment and analysis of volumetric images already available in the project (segmentation, calculation of volume, registration). The results obtained have lead to the development of methods for quantitative evaluation of the effects of medication over time.

A second contract in 1999 will enable this research to continue.

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