K M Cecil and R E Lenkinski.
Proton MR spectroscopy in inflammatory and infectious brain disorders.
Neuroimaging Clin N Am,
8(4):863-80,
November 1998.
Keywords:
AIDS Dementia Complex,
diagnosis,
Brain Abscess,
diagnosis,
Brain Diseases,
diagnosis,
Creutzfeldt-Jakob Syndrome,
diagnosis,
Herpes Simplex,
diagnosis,
Human,
Magnetic Resonance Spectroscopy,
Support U.S. Gov't P.H.S.,
Tuberculoma,
diagnosis.
| Abstract: |
This article reviews the proton MR spectroscopy literature regarding brain infarction and inflammatory diseases. We examine the salient findings reported for bacterial abscesses, intracranial tuberculomas, Creutzfeldt-Jakob disease, herpes simplex encephalitis and HIV. These processes demonstrate specific metabolic profiles which may be useful in differential diagnosis. The results reported in the literature support the view that MR spectroscopy can be employed in longitudinal studies to monitor the response to therapy and therefore may lead to individual optimized treatment effectiveness. |
@ARTICLE{cecil:ncna:1998,
AUTHOR = {K M Cecil and R E Lenkinski},
JOURNAL = {Neuroimaging Clin N Am},
TITLE = {Proton MR spectroscopy in inflammatory and infectious brain disorders},
YEAR = {1998},
MONTH = {November},
OPTNOTE = {},
NUMBER = {4},
PAGES = {863-80},
VOLUME = {8},
KEYWORDS = {AIDS Dementia Complex, diagnosis, Brain Abscess, diagnosis, Brain Diseases, diagnosis, Creutzfeldt-Jakob Syndrome, diagnosis, Herpes Simplex, diagnosis, Human, Magnetic Resonance Spectroscopy, Support U.S. Gov't P.H.S., Tuberculoma, diagnosis},
ABSTRACT = {This article reviews the proton MR spectroscopy literature regarding brain infarction and inflammatory diseases. We examine the salient findings reported for bacterial abscesses, intracranial tuberculomas, Creutzfeldt-Jakob disease, herpes simplex encephalitis and HIV. These processes demonstrate specific metabolic profiles which may be useful in differential diagnosis. The results reported in the literature support the view that MR spectroscopy can be employed in longitudinal studies to monitor the response to therapy and therefore may lead to individual optimized treatment effectiveness.}
}
S Peled,
H Gudbjartsson,
C F Westin,
R Kikinis,
and F A Jolesz.
Magnetic resonance imaging shows orientation and asymmetry of white matter fiber tracts.
Brain Res,
780(1):27-33,
January 1998.
Keywords:
Anisotropy,
Brain Mapping,
methods,
Diffusion,
Female,
Human,
In Vitro,
Laterality,
physiology,
Linear Models,
Magnetic Resonance Imaging,
Male,
Nerve Fibers,
pathology,
Neural Pathways,
physiology,
Reference Values,
Support Non-U.S. Gov't,
Support U.S. Gov't P.H.S..
| Abstract: |
Apparent diffusion tensor maps of the human brain were acquired with a magnetic resonance imaging sequence (Gudbjartsson, H., Maier, S.E., Mulkern, R.V., M6rocz, I.A., Patz, S., Jolesz, F.A., Magn. Reson. Med. 36 (1996) 509-519). It was shown that the geometric nature of the apparent diffusion tensors can quantitatively characterize the tissue structure. Display of the orientation and directional uniformity of the water diffusion in the brain demonstrated most of the known major anatomical constituents of human white matter. A comparison of corresponding anatomic regions in the white matter of both hemispheres in 24 healthy volunteers revealed that fiber tracts within the anterior limb of the internal capsule have a significantly higher (P < 0.01) measure of alignment in the right hemisphere. This method offers a unique tool for the in vivo demonstration of neural connectivity in healthy and diseased brain. |
@ARTICLE{peled:br:1998,
AUTHOR = {S Peled and H Gudbjartsson and C F Westin and R Kikinis and F A Jolesz},
JOURNAL = {Brain Res},
TITLE = {Magnetic resonance imaging shows orientation and asymmetry of white matter fiber tracts},
YEAR = {1998},
MONTH = {January},
OPTNOTE = {},
NUMBER = {1},
PAGES = {27-33},
VOLUME = {780},
KEYWORDS = {Anisotropy, Brain Mapping, methods, Diffusion, Female, Human, In Vitro, Laterality, physiology, Linear Models, Magnetic Resonance Imaging, Male, Nerve Fibers, pathology, Neural Pathways, physiology, Reference Values, Support Non-U.S. Gov't, Support U.S. Gov't P.H.S.},
ABSTRACT = {Apparent diffusion tensor maps of the human brain were acquired with a magnetic resonance imaging sequence (Gudbjartsson, H., Maier, S.E., Mulkern, R.V., M6rocz, I.A., Patz, S., Jolesz, F.A., Magn. Reson. Med. 36 (1996) 509-519). It was shown that the geometric nature of the apparent diffusion tensors can quantitatively characterize the tissue structure. Display of the orientation and directional uniformity of the water diffusion in the brain demonstrated most of the known major anatomical constituents of human white matter. A comparison of corresponding anatomic regions in the white matter of both hemispheres in 24 healthy volunteers revealed that fiber tracts within the anterior limb of the internal capsule have a significantly higher (P < 0.01) measure of alignment in the right hemisphere. This method offers a unique tool for the in vivo demonstration of neural connectivity in healthy and diseased brain.}
}